Before You Continue...

A first step as you consider this study is to answer a 5-minute online questionnaire about your health and medical history. If your answers show the study might be a good fit for you, you may choose to be referred to a study clinic that you select. You will then be asked to provide your contact information for a study representative to contact you and discuss the next steps. Only the study staff can determine if you meet the study's eligibility criteria and are able to enroll in the study.

Click 'Next' to begin the questionnaire.

Question 1 of 4
Question 2 of 4
Have you received a flu vaccine in the last 6 months?
Question 3 of 4
Have you received an mRNA-based COVID vaccine or booster in the last 14 days?
Question 4 of 4
Do you have a chronic medical condition that has required a change in therapy or hospitalization over the past 6 weeks?

Sorry, you are not eligible or we may not be recruiting your age group at this time...

Thank you so much for your interest in the mRNA flu vaccine study and for answering our questions.

There may be other Pfizer research studies enrolling in your area in the future. If you would like to be notified about future research opportunities, we will collect your name, phone number, and email address so that a study representative may contact you about other research studies. Your contact information will not be used for any other purposes.

The individual responses you've provided will be used by Pfizer, or our partners supporting this study, to look for areas of improvement such as revising the criteria for participation in this study. Pfizer study team members and our partners will have access to reports containing aggregated data that will not be directly linked back to you. All information is stored on servers in the United States.

So far, so good!

Please enter your information below to find a study location near you. By doing so, you also opt-in to be contacted about other future Pfizer studies. Once you select a site, the research study staff will contact you to see if you qualify to enroll.

Choose a Location
See below to select a research site near you. If you don't see a site near you, select "The sites listed here are not convenient for me." Study locations are added regularly. A study representative will contact you if a research site becomes available in your area.

Accel Research Sites | Lakeland

2135 Harden Boulevard
Lakeland, FL 33803
NaN Mi

Accel Research Sites, Maitland CRU

2300 Maitland Center Parkway, Suite 230
Maitland, FL 32751
NaN Mi

Accellacare - Bristol

350 Steeles Road
Bristol, TN 37620
NaN Mi

Accellacare - Charlotte

1700 Abbey Place, Suite 201
Charlotte, NC 28209
NaN Mi

Accellacare - Salisbury

410 Mocksville Avenue
Salisbury, NC 28144
NaN Mi

Accellacare - Wilmington

1202 Medical Center Drive
Wilmington, NC 28401
NaN Mi

Accellacare DuPage

4061 W 95th Street
Oak Lawn, IL 60453
NaN Mi

The sites listed here are not convenient for me.

Sorry, you are not eligible or we may not be recruiting your age group at this time...

Please enter your information below if you would like to be contacted about future clinical research opportunities.

First name must not be blank

Last name must not be blank

Please enter a valid phone number

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Please select a valid address

About the mRNA Flu Vaccine Phase 3 Study

Today's flu vaccines are updated each year to prevent infection with the specific strains of the flu that scientists and health officials expect to be common that year. It takes several months to make the vaccines and their effectiveness depends on how well they match the strains of the flu virus that are circulating.

Recent advances in mRNA-based vaccines, like the COVID-19 vaccine, have taught us more about how mRNA technology can be used to develop vaccines. mRNA vaccines take less time to make. This means it could be easier to produce vaccines each season that are better matched to the most common flu strains.

The creation of the COVID-19 vaccine made history. Could you help us try to do it again with flu?

This study will help us learn if an investigational vaccine is safe and can help the body produce antibodies which may help fight off the flu. The investigational vaccine is thought to work by activating your immune system using mRNA. There is no weakened or dead flu virus in the investigational vaccine.

Your participation in this research study will not only help advance a potential new type of flu vaccine, but will support investigational vaccine development for other infectious diseases. So, thank you for taking the time to learn more.

This study is enrolling people who:

  • Are at least 18 years old
  • Are generally healthy or have stable chronic conditions
  • Have not received an investigational or licensed flu vaccine in the last six months

This study will include people from two different age groups — 18 to 64 and 65 or older. We are currently accepting referrals who are 18 or older and invite you to complete our online questionnaire to see if you may be able to participate.

Be Represented

While everyone needs to be represented in vaccine clinical studies, it is especially important that these vaccine studies include people from the communities most significantly impacted by the flu. By choosing to volunteer, you will represent people like you — in age, sex, race, and ethnicity and from communities like yours. Involving people from all backgrounds will improve the development of this investigational vaccine for everyone. By volunteering for a flu vaccine study, you can make a difference.

About mRNA Vaccines

The immune system is the body's natural defense against infections. Vaccines help the immune system recognize viruses and bacteria that may invade the body in the future.

Some vaccines contain a small amount of the virus or bacteria from the disease they are designed to help prevent. The virus or bacteria has either been killed or weakened so it cannot make a person sick. Other vaccines contain only a part of the germ from the disease.

The investigational vaccine being studied is a mRNA vaccine, which does not contain any killed or weakened virus. mRNA vaccines work by telling your body to produce proteins that look just like certain parts of the virus. The immune system reacts to these proteins in a similar way to a real virus. As a result, certain immune system cells "remember" how to recognize these proteins quickly and fight the real infection if it happens in the future.

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What To Expect


Study participants will receive the investigational flu vaccine or a licensed flu vaccine. Participants have an equal chance of receiving either the investigational vaccine or the licensed flu vaccine.


This research study will last about six months. Participants will visit the research site at least three times, including a vaccination visit and two follow-up visits to monitor their health.

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Over the course of the study, participants will need to report any changes in their health. To make this easier, they will be given an electronic diary (eDiary) to use, or they can download the secure eDiary app to their smartphone.


The study vaccine and study-related procedures will be provided at no cost. Participants do not need health insurance to take part. Participants will be reimbursed for any reasonable expenses they have as a result of being in this study. This may include parking, meals, or other travel related expenses.


Research studies are voluntary. Taking part in a research study is a personal choice. Participants may leave the study at any time and for any reason.

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