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Please enter your information below to find a study location near you. By doing so, you also opt-in to be contacted about future Pfizer studies. Once you select a site, the research study staff will contact you to see if you qualify to enroll.

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Please enter your information below if you would like to be contacted about future clinical research opportunities.

Could you be part of the next vaccine breakthrough?

Introducing a research study for an investigational mRNA flu vaccine

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Before You Continue...

The following questions are voluntary and will take approximately 5 minutes to complete. These questions are designed to evaluate if you are potentially eligible to participate in this study. We will ask questions about your health and some questions may be personal in nature. You may choose to stop the questionnaire at any time. Completing this questionnaire does not mean that you are eligible to enroll in a Pfizer clinical trial as only the research staff can determine if you qualify to enroll in the study.

If you would like to proceed with taking the questionnaire, you may click ‘Next’.

Question 1 of 4

Are you 65 to 85 years old?

Question 2 of 4

Have you received a flu (influenza) vaccine in the last 6 months?

Question 3 of 4

Have you received a COVID vaccine in the last 2 months?

Question 4 of 4

Do you have a chronic medical condition that has required a change in therapy or hospitalization over the past 6 weeks?

So far, so good!

You appear to meet the basic requirements for this flu vaccine study. Respondents who prequalify and choose to be referred to the study location they select will have their contact information as well as their responses to questions recorded and shared with the research team as well as those working on their behalf. It is necessary to collect your name, phone number, and email address so the research staff may contact you to discuss next steps regarding your potential enrollment in this study. Your contact information will not be used for any other purpose.

The individual responses you’ve provided will be used by Pfizer, or our partners supporting this study to analyze and evaluate this study for areas of improvement such as revising study criteria for participation. Pfizer study team members and our partners will have access to reports containing only aggregated data that will not be directly attributable back to an individual. All information is stored on servers in the United States.

Sorry, you are not eligible at this time...

Thank you so much for your interest in the mRNA flu vaccine study and for answering our questions.

There may be other research studies enrolling in your area in the future. Respondents who are interested in being contacted about future research opportunities will have their contact information as well as their responses to questions recorded and shared with the research team as well as those working on their behalf. It is necessary to collect your name, phone number, and email address so the research staff may contact you about other research studies. Your contact information will not be used for any other purpose.

The individual responses you’ve provided will be used by Pfizer or our partners supporting this study to analyze and evaluate this study for areas of improvement such as revising study criteria for participation. Pfizer study team members and our partners will have access to reports containing only aggregated data that will not be directly attributable back to an individual. All information is stored on servers in the United States.

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Choose a Location

See below to select a research site near you. If you don’t see a site near you, select "The sites listed here are not convenient for me." Study locations are added regularly. A study representative will contact you if a research site becomes available in your area.

The sites listed here are not convenient for me.

About the mRNA Flu Vaccine Study

Today’s flu vaccines are updated each year to prevent infection with the specific strains of the flu that scientists and health officials expect to be common that year. It takes several months to make the vaccines and their effectiveness depends on how well they match the strains of the flu virus that are circulating.

With the recent advancement of COVID-19 vaccines based on mRNA technology, we’ve learned that mRNA vaccines can potentially be developed much more quickly and may be better matched to each season’s specific strains.

The creation of the COVID-19 vaccine made history. Could you help us try to do it again with flu?

The mRNA Flu Vaccine Study will help us learn if an investigational vaccine is safe and can help the body produce antibodies which may help fight off the flu. The investigational vaccine is thought to work by activating your immune system using mRNA. There is no weakened or dead flu virus in the investigational vaccine.

This study will enroll about 615 people in the United States.

Your participation in this research study can help advance a potential new type of flu vaccine. So, thank you for taking the time to learn more.

This study is enrolling people who:

  • Are 65 to 85 years old
  • Are generally healthy or have stable chronic conditions
  • Have not had a flu vaccine in the last six months
  • Have not had a COVID-19 vaccine in the last two months

Be Represented

While everyone needs to be represented in vaccine clinical studies, it is especially important that these vaccine studies include people from the communities most significantly impacted by the flu. By choosing to volunteer, you will represent people like you—in age, sex, race, and ethnicity and from communities like yours. Involving people from all backgrounds will improve the development of this investigational vaccine for everyone. By volunteering for a flu vaccine study, you can make a difference.

About mRNA Vaccines

The immune system is the body’s natural defense against infections. Vaccines help the immune system recognize bacteria or viruses that may invade the body in the future.

Some vaccines contain a small amount of the bacteria or virus from the disease they are designed to help prevent. The virus has either been killed or weakened so it cannot make a person sick. Other vaccines contain only a part of the germ from the disease.

The investigational vaccine being studied is a mRNA vaccine, which does not contain any killed or weakened virus. mRNA vaccines work by telling your body to produce proteins that look just like certain parts of the bacteria or virus. The immune system reacts to these proteins in a similar way to a real infection, but without the sickness that goes with it. As a result, certain immune system cells “remember” how to recognize these proteins quickly and fight the real infection if it happens in the future.

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What to Expect

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Study participants will receive the investigational vaccine or a publicly available flu vaccine. Participants who receive the investigational vaccine will be given the opportunity to receive the publicly available flu vaccine before the end of the study.

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This research study will last six months. Participants will visit the research site six times—once for a screening visit, once for the vaccination visit, and four more times for follow-up visits after vaccination to monitor their health. Participants will also be contacted at home by telephone approximately six months after the vaccination to ask about their health.

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Over the course of the study, participants will need to report any changes in their health. To make this easier, they will be given an electronic diary (eDiary) to use, or they can download the secure eDiary app to their smartphone.

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The study vaccine and study-related procedures are generally covered at no cost. Participants do not need health insurance to take part. Participants will be reimbursed for any reasonable expenses they have as a result of being in this study. This may include parking, meals, or other travel related expenses.

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Research studies are voluntary. Taking part in a research study is a personal choice. Participants may leave the study at any time and for any reason.