About the mRNA Flu Vaccine Study

So far, so good!

Please enter your information below to find a study location near you. By doing so, you also opt-in to be contacted about other future Pfizer studies. Once you select a site, the research study staff will contact you to see if you qualify to enroll.

Sorry, you are not eligible at this time...

Please enter your information below if you would like to be contacted about future clinical research opportunities.

Could you be part of the next vaccine breakthrough?

Introducing a research study for an investigational mRNA flu vaccine

Get Started

Before You Continue...

The following questions are voluntary and will take approximately 5 minutes to complete. These questions are designed to evaluate if you are potentially eligible to participate in this study. We will ask questions about your health and some questions may be personal in nature. You may choose to stop the questionnaire at any time. Completing this questionnaire does not mean that you are eligible to enroll in a Pfizer clinical trial as only the research staff can determine if you qualify to enroll in the study.

If you would like to proceed with taking the questionnaire, you may click 'Next'.

Question 1 of 4

Are you 65 to 85 years old?

Yes

Question 2 of 4

Have you received this year's flu vaccine at least 4 months ago?

Yes

Question 3 of 4

Have you received a COVID vaccine or booster in the last month?

Yes

Question 4 of 4

Do you have a chronic medical condition that has required a change in therapy or hospitalization over the past 6 weeks?

Yes

So far, so good!

You appear to meet the basic requirements for this flu vaccine study. Respondents who prequalify and choose to be referred to the study location they select will have their contact information as well as their responses to questions recorded and shared with the research team as well as those working on their behalf. It is necessary to collect your name, phone number, and email address so the research staff may contact you to discuss next steps regarding your potential enrollment in this study. Your contact information will not be used for any other purposes.

The individual responses you've provided will be used by Pfizer, or our partners supporting this study to analyze and evaluate this study for areas of improvement such as revising study criteria for participation. Pfizer study team members and our partners will have access to reports containing only aggregated data that will not be directly attributable back to an individual. All information is stored on servers in the United States.

Sorry, you are not eligible at this time...

Thank you so much for your interest in the mRNA flu vaccine study and for answering our questions.

There may be other Pfizer research studies enrolling in your area in the future. Respondents who are interested in being contacted about future research opportunities will have their contact information as well as their responses to questions recorded and shared with the research team as well as those working on their behalf. It is necessary to collect your name, phone number, and email address so the research staff may contact you about other research studies. Your contact information will not be used for any other purposes.

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Choose a Location

See below to select a research site near you. If you don’t see a site near you, select "The sites listed here are not convenient for me." Study locations are added regularly. A study representative will contact you if a research site becomes available in your area.

The sites listed here are not convenient for me.

About the mRNA Flu Vaccine Study

Today’s flu vaccines are updated each year to prevent infection with the specific strains of the flu that scientists and health officials expect to be common that year. It takes several months to make the vaccines and their effectiveness depends on how well they match the strains of the flu virus that are circulating.

With the recent advancement of COVID-19 vaccines based on mRNA technology, we’ve learned that mRNA vaccines can potentially be developed much more quickly and may be better matched to each season’s specific strains.

The creation of the COVID-19 vaccine made history. Could you help us try to do it again with flu?

The mRNA Flu Vaccine Study will help us learn if an investigational vaccine is safe and can help the body produce antibodies which may help fight off the flu. The investigational vaccine is thought to work by activating your immune system using mRNA. There is no weakened or dead flu virus in the investigational vaccine.

Your participation in this research study will not only help advance a potential new type of flu vaccine, but will support investigational vaccine development for other infectious diseases. So, thank you for taking the time to learn more.

This study is currently enrolling people who:

Are 65 to 85 years old
Are generally healthy or have stable chronic conditions
Have already received this year’s flu vaccine more than four months ago
Have not received a COVID-19 vaccine in the last month

Be Represented

While everyone needs to be represented in vaccine clinical studies, it is especially important that these vaccine studies include people from the communities most significantly impacted by the flu. By choosing to volunteer, you will represent people like you—in age, sex, race, and ethnicity and from communities like yours. Involving people from all backgrounds will improve the development of this investigational vaccine for everyone. By volunteering for a flu vaccine study, you can make a difference.

About mRNA Vaccines

The immune system is the body’s natural defense against infections. Vaccines help the immune system recognize viruses and bacteria that may invade the body in the future.

Some vaccines contain a small amount of the virus or bacteria from the disease they are designed to help prevent. The virus or bacteria has either been killed or weakened so it cannot make a person sick. Other vaccines contain only a part of the germ from the disease.

The investigational vaccine being studied is a mRNA vaccine, which does not contain any killed or weakened virus. mRNA vaccines work by telling your body to produce proteins that look just like certain parts of the virus. The immune system reacts to these proteins in a similar way to a real virus. As a result, certain immune system cells “remember” how to recognize these proteins quickly and fight the real infection if it happens in the future.

What to Expect

Study participants will receive the investigational flu vaccine, a licensed flu vaccine, or both.

This research study will last about eight months. Participants will visit the research site up to eight times, including screening, vaccination, and follow-up visits to monitor their health. Participants will also be contacted at home by telephone approximately six months after their last vaccination to ask about their health.

Over the course of the study, participants will need to report any changes in their health. To make this easier, they will be given an electronic diary (eDiary) to use, or they can download the secure eDiary app to their smartphone.

The study vaccine and study-related procedures will be provided. Participants do not need health insurance to take part. Participants will be reimbursed for any reasonable expenses they have as a result of being in this study. This may include parking, meals, or other travel related expenses.

Research studies are voluntary. Taking part in a research study is a personal choice. Participants may leave the study at any time and for any reason.